CBD has lately surpassed other kinds of natural medicines, with it rapidly becoming many individuals’ favourite. As a result, there has been an increase in CBD and its potential health advantages research. Buy different CBD products with marijuana delivery Toronto.
Cannabidiol is said to be beneficial to the immune system and is frequently recommended as a natural daily supplement. However, there is still a lot of uncertainty about cannabidiol’s potential to aid with some of today’s most pressing health issues, such as Alzheimer’s disease.
CBD has the potential to alter how we deal with a variety of issues, including Alzheimer’s disease.
The use of CBD has shown promise in the treatment of Alzheimer’s disease, however further research is needed. It is expected that CBD will change how we react to the condition in the future. Before we go through exactly how CBD may assist those with Alzheimer’s disease, let’s first define it.
- 1 What Is Alzheimer’s Disease?
- 2 How Is CBD Thought to Affect Alzheimer’s Disease?
- 3 Recent Research into CBD & Alzheimer’s
- 4 How Does CBD Compare to Other Medications?
- 5 What Type of CBD Oil to Get for Alzheimer’s?
- 6 Recommended Dosage of CBD Oil for Alzheimer’s
- 7 Does CBD Oil for Alzheimer’s Carry Any Side Effects?
- 8 Final Thoughts on CBD and Alzheimer’s Disease
What Is Alzheimer’s Disease?
Alzheimer’s disease and dementia are frequently confused by people. The terms are sometimes interchangeable when it comes to Alzheimer’s disease and dementia. Dementia is a catchall term that covers a variety of memory-related illnesses. It can be caused by a variety of things, including aging, illness, or injury, to the point that it interferes with a person’s capacity to pursue typical daily activities.
Dementia is a term that describes a group of symptoms that include memory loss and difficulties with thinking, problem-solving, or language. This might be the case due to brain damage caused by oxygen deprivation, such as in the instance of a heart attack. It might also be brought on by an illness like Alzheimer’s disease.
In a nutshell: dementia is a more general term that refers to cognitive deterioration, while Alzheimer’s disease is only one of the possible causes.
The brain is a highly complicated system made up of billions of nerve cells that interact and communicate with one another. Beta-amyloid, along with tau protein buildup, causes neurons to lose their connections and function. This most definitely affects how neurons communicate with each other.
The protein builds up in the brain when it is not correctly broken down, and this may result in clumps (plaques and tangles) that most certainly lead to neurons failing to get required neurotransmitters. In Alzheimer’s disease patients, signaling chemicals that enable information to travel between neurons are significantly reduced. This reduces the brain’s capacity to function at peak efficiency.
Alzheimer’s disease is a progressive illness in which the symptoms worsen over time as more cells are damaged and killed. Patients ultimately lose so many cells that everything about their daily routine, including their motor coordination, language, memory recall, and personality, is altered.
Alzheimer’s Disease: Signs and Symptoms
Alzheimer’s disease remains a mystery in terms of its origin, making it difficult to determine who is most vulnerable and what risk treatments are effective. The majority of cases occur in people over the age of 65, although a significant number of individuals under that age have some form of early-onset dementia.
Unfortunately, there isn’t much that someone can do to lower their chance of getting Alzheimer’s disease. The Alzheimer’s Society recommends the following as potentially helpful:
- Leading a healthy lifestyle
- Eating a balanced diet
- Limiting alcohol intake
- Staying mentally and socially active
Memory loss and learning difficulties are among the first indications of Alzheimer’s disease. This is due to the fact that, in most cases, the hippocampus is the first section of the brain to be affected by dementia.
The hippocampus is home to the greatest number of naturally occurring cannabinoids, according to several studies. This information has prompted numerous research on whether CBD may benefit the hippocampus and, as a result, Alzheimer’s disease.
Let’s see if CBD has the ability to prevent Alzheimer’s disease from progressing.
How Is CBD Thought to Affect Alzheimer’s Disease?
CBD, as shown in various research, has anti-inflammatory and antioxidant properties that are well documented. This fundamental concept has resulted in a significant amount of study throughout the world to figure out how CBD works in the brain of someone who has Alzheimer’s disease.
In 2004, a research was conducted on rats in the Journal of Neurochemistry that examined the effect of CBD on cells differentiated from rat brain tissue. CBD was found to have protective effects on the cells in this study.
A study published in the Journal of Frontiers in Pharmacology in 2017 found that some research supports the notion that CBD can stimulate brain cell growth. When CBD was administered to Alzheimer’s disease rats, it was shown to delay memory and cognitive impairment.
Recent Research into CBD & Alzheimer’s
In 2019, a study published in the Journal of Pharmacopuncture investigated the effects of THC and CBD on Alzheimer’s disease. The researchers noted that CBD might aid in the treatment and prevention of Alzheimer’s disease.
According to them, CBD components may help manage a variety of symptoms including memory loss and behavioral disorders. However, current evidence suggests that combining CBD with THC works better than using THC or CBD alone.
A study published in the Journal of Alzheimer’s Disease in 2021 revealed that high doses of CBD helped boost memory and decrease beta-amyloid plaque accumulation in an animal model.
Furthermore, CBD boosted levels of the IL-33 protein sevenfold and TREM2 tenfold. Both proteins are crucial since they aid immune cells in the brain in getting rid of dead cells and debris, including beta-amyloid plaque, which forms in Alzheimer’s patients’ brains. The amounts of both IL-33 and TREM2 have decreased in the brains of individuals with Alzheimer’s disease. The investigators explain that the next phases include determining the most effective doses to administer. They also want to evaluate the effect of starting CBD treatment earlier in the Alzheimer’s disease cycle.
CBD is also used to relieve anxiety and stress. These are two common symptoms of Alzheimer’s disease, which are associated with the patient’s declining knowledge and connection with their surroundings.
This may not seem to have an impact on how Alzheimer’s disease develops over time, but attempting to relieve these symptoms can make life seem a bit easier for someone who is dealing with Alzheimer’s-related anxiety.
How Does CBD Compare to Other Medications?
Alzheimer’s disease is characterized by memory loss and a decline in intellectual capacity. There are several different therapies for this condition. While none of them will reverse or entirely stop the symptoms from worsening, they may minimize its impact.
When it comes to Alzheimer’s disease, however, medication can target specific symptoms in order to make life seem a little more manageable. This is comparable to how a painkiller might be used to make the effects of a headache more bearable.
Donepezil, rivastigmine, and galantamine are the three most common Alzheimer’s disease drugs prescribed to patients in the early to mid-stages of their disease.
All three of these drugs have different influences and are suited to various people, although they all enhance brain chemical messengers. This leads to improved attention and motivation as well as aiding the body in remembering things. These medicines may also be beneficial for persons who suffer from Alzheimer’s disease-related panic attacks.
The bigger issue is whether or not CBD may be utilized to slow down the development of Alzheimer’s disease in the same way that prescription drugs can.
There are a lot of people that don’t know what CBD is. The United States Drug Enforcement Administration banned the substance in November, 2018. Many people aren’t even aware that it exists because it has gotten so little media exposure. Researchers around the world are continuously searching for an answer to this problem. They’re hoping CBD may be able to provide one for what is becoming an increasingly serious health issue.
What Type of CBD Oil to Get for Alzheimer’s?
There is no one-size-fits-all CBD product for Alzheimer’s patients. Because the cannabidiol market is expanding, there are many alternatives. The following are some of the most popular items on the market:
- CBD oil
- CBD pills
- CBD gummies
- CBD topicals
- CBD vape juice
- CBD patches
Those caring for Alzheimer’s patients might find it easier to administer it in CBD gummy form. However, it is also possible to add CBD oil drops to a patient’s food or drink. One of the advantages of CBD gummies is that the dosage of the cannabinoid is easy to measure. High-quality CBD brands that sell gummies include:
- Joy Organics
- Medix CBD
- Try The CBD
Recommended Dosage of CBD Oil for Alzheimer’s
Because there has been so little study of CBD oil for Alzheimer’s, it is difficult to give precise dosing instructions. However, we may examine relevant research and analyze the dosages used by researchers in order to learn more about them.
For example, a research published in Medical Cannabis and Cannabinoids in 2019 investigated the impact of an orally ingested CBD/THC pill on individuals with dementia. On average, ten people with dementia took the following daily dosages of CBD and THC:
- 2mg CBD and 7.6mg THC
- 6mg CBD and 8.8mg THC
- 18mg CBD and 9mg THC
The greatest daily dosage taken was 26 mg CBD and 13 mg THC. During the study, half of the participants stopped taking other psychotropic medicines or stopped using them entirely. The researchers found that the patients had fewer behavioral issues and improved rigidity scores, in addition to no medication refusal owing to side effects.
Does CBD Oil for Alzheimer’s Carry Any Side Effects?
In general, CBD’s adverse effects are minor. In 2017, a study was published in Cannabis and Cannabinoid Research describing the following side effects:
- Appetite changes
- Changes in weight
Drug interactions with drug-metabolizing enzymes such as those found in the cytochrome P450 family are possible. CBD is metabolized by CYP3A4. Ritonavir and itraconazole inhibit this enzyme, which causes problems when taking CBD together with these medications.
However, CBD has been found to have little or no negative effects in most individuals, even at dosages of up to 1,500mg per day.
Final Thoughts on CBD and Alzheimer’s Disease
While there is a lot of work left to be done on Alzheimer’s disease and its causes, progress has been made. Researchers must also look into how CBD may aid in the slowing down and alleviation of symptoms.
According to study, there are numerous reasons to take CBD supplements. Even if it’s just a supplement, there are several advantages to taking CBD. However, before using CBD while on other medications, individuals should first check with their doctor to avoid any unwanted side effects.